張才喬,浙江大學動物科學院副所長、教授、博導。研究方向:動物生理生化、繁殖生理學。
一、教授課程
本科
1、動物生理學(必修課,省級精品課程,3學分)
2、動物細胞生物學(選修課,2學分)
張才喬,浙江大學動物科學院教授、博導,動物生化繁殖專家。
碩士
1、動物細胞與發育生物學(博士生學位課,校核心課,2學分)
2、獸醫科學進展(碩士生學位課,2學分)
3、動物分子細胞生物學實驗技術(碩士生學位課,2學分)
4、動物生物化學專題(碩士生學位課,2學分)
5、高階動物生理及病理學(碩士生學位課,2學分)
6、基礎獸醫學專題(全日制專業學位碩士生學位課,3學分)
7、基礎獸醫學專題(非全日制專業學位碩士生學位課,3學分)
8、實驗設計與科技寫作(專業學位碩士生學位課,2學分)
浙江大學
二、科研專案
研究內容
1、生殖幹細胞發育調控機理的研究
2、禽類卵泡發育和閉鎖及產蛋機能調節
3、內分泌干擾物生殖毒性作用及其分子機理的研究
4、禽類生物反應器平臺的研究機制和防治措施的研究
主持
1、專案名稱:母雞卵巢內細胞間互作對原始卵泡發生及其發育的調節作用,國家自然科學基金(31772693),2018.01.-2022.12.
2、專案名稱:母雞小黃卵泡庫動態變化調節機理的研究,國家自然科學基金(31472160),2015.01.-2018.12.
3、專案名稱:蛋雞卵泡再生和閉鎖調控機理的研究,國家自然科學基金(31272525),2013.01.-2016.12.
4、專案名稱:雌激素透過膜受體GPR30調節雞胚PGC發育及其機理的研究. 高等學校博士學科點專項科研基金(20110101110099),2012.01-2014.12.
5、專案名稱:家禽肝-卵巢軸對卵黃沉積和胚胎髮育調控作用的研究. 浙江省自然科學基金重點專案(Z3110115),2011.01-2013.12.
6、專案名稱:作物新品種培育及動物消化系統研究. 浙江大學校長基金子課題(2011XZZX006),2011.01-2013.12.
7、專案名稱:間充質幹細胞移植對小鼠肝硬化修復作用的研究. 傳染病診治國家重點實驗室開放基金(2010KF03),2010.06-2012.12.
8、專案名稱:家禽卵泡內區域性訊號通訊對等級前卵泡發育調控機理的研究,國家自然科學基金(30871843),2009.01.-2011.12.
9、專案名稱:原始生殖細胞介導的家禽生物反應器的構建,浙江省科技支撐和引導計劃面上專案(2008C22040),2008.01-2009.12.
10、專案名稱:禽類生殖幹細胞為載體的生物反應器平臺的研究,教育部“新世紀優秀人才支援計劃”(NCET-05-0514),2006.01-2008.12.
11、專案名稱:體細胞誘導的胚胎生殖幹細胞增殖和分化機制的研究,國家自然科學基金(30471245),2005.01.-2007.12.
12、專案名稱:下丘腦和腺垂體細胞聯合移植對家雞繁殖機能的影響及其機理的研究,國家自然科學基金(30371051),2004.01.-2006.12.
13、專案名稱:母雞性行為反轉機制的研究,國家自然科學基金(39970535),2000.1.-2002.12.
張才喬教授在廣西大學做題為“家禽性分化和生殖細胞發育的激素調節”的報告。
三、研究成果
承擔8項國家自然科學基金的研究、、3項浙江省自然科學基金和2項浙江省科技廳專案的研究。在家禽繁殖生理和毒理及生物技術方面取得了一系列新成果,發表論文100餘篇,申報專利1項。
(此處已新增圈子卡片,請到今日頭條客戶端檢視)
四、著作教材
1、張才喬 主譯. 《Avian Physiology 6th edition》,中國農業出版社,“十二五”國家重點圖書出版規劃專案世界獸醫經典著作譯叢
2、張才喬 主編. 《動物生理學實驗》,第二版,科學出版社, 全國高等農林院校規劃教材,2014年,ISBN 978-7-03-040968-3
3、張才喬 副主譯. 《Dukes′ Physiology of Domestic Animals》,第十二版,中國農業出版社,“十二五”國家重點圖書出版規劃專案世界獸醫經典著作譯叢,2014.5,ISBN 978-7-109-17675-1
4、張才喬 副主編. 《動物生理學》,第二版,科學出版社, 全國高等農林院校規劃教材,2012年1月,普通高等教育“十二五”規劃教材,978-7-03-033315-5
5、張才喬 副主編.《動物生理學》,第五版,中國農業出版社, 普通高等教育“十一五”國家級規劃教材、全國高等農業院校“十一五”規劃教材,2011.7出版,ISBN 978-7-10-915809-2
浙江大學
五、獲獎情況
1、浙江省“新世紀151人才工程”第二層次培養人員,2010
2、2010年校級先進工作者
3、《產蛋雞卵泡發育的組織學結構的研究》,中國畜牧獸醫學會動物解剖與組織胚胎學分會第十六次學術研討會優秀論文獎,青海西寧,2010
4、2009年度浙江大學本科生百篇特優畢業論文(設計)優秀指導教師
5、浙江大學“聖雄學生工作管理獎教金”獲得者,2009年
6、《動物生理學》省級精品課程,2009年
7、全國優秀博士學位論文提名論文,黃酮類化合物緩解內分泌干擾物引起的雄性雞胚生殖毒性機理的研究,教育部,博士生:米玉玲,導師:張才喬,2008年
8、浙江大學教學成果二等獎,“農科“動物生理學”課程教學體系的改革”,2008
9、入選“浙江大學首屆教學名師培養物件”,2008年
10、2008年度獎教金獲得者
11、浙江省自然科學優秀論文一等獎,“槲皮素對多氯聯苯引起的雞胚精原細胞氧化損傷的緩解作用”,2007
12、2007年院級、校級先進工作者
13、教育部“新世紀優秀人才支援計劃”獲得者,2006-2008
14、浙江省自然科學基金人才培養專案獲得者,2006-2008
15、浙江省“新世紀151人才工程”第三層次培養人員,2005年
16、浙江省高校優秀科研成果二等獎,“環境內分泌干擾物生物活性評價細胞模型的建立及其應用”,2005
17、浙江省自然科學優秀論文二等獎,“多氯聯苯對培養的雞胚卵巢生殖細胞增殖的雌激素和毒性作用”2005
18、浙江大學優秀教師獎,2004
19、浙江大學教學成果二等獎,“動物生理學實驗教學創新體系構建”,2004年,排名1/3
20、浙江省自然科學優秀論文二等獎,“多氯聯苯對雞胚性腺發育和生殖功能的干擾作用”,2003
六、論文
1、Xingting Liu, Xin Lin, Siyu Zhang, Changquan Guo, Jian Li, Yuling Mi*, Caiqiao Zhang* Lycopene ameliorates oxidative stress via activation of Nrf2/HO-1 pathway in the aging chicken ovary. Aging-US. 2018,10(8):2016-2036. https://doi.org/10.18632/aging.101526
2、Lijuan Liu; Siyu Zhang; Jiayang Bao; Xiaowen He; Danni Tong; Cong Chen; Qingxiang Ying; Qing Zhang; Caiqiao Zhang*; Jian Li*. Melatonin improve hens laying performance by regulating intestinal amino acids transportation. Frontiers in Endocrinology, section Experimental Endocrinology. 2018 Manuscript ID: 384996
3、Min Xiao; Yuling Mi; Caifeng Lv; Weidong Zeng; Caiqiao Zhang*; Jian Li*. Taurine regulate mucosal renewal to alleviate LPS-induced duodenal inflammation. Amino Acids. 2018,50(11):1637-1646
4、Xin Lin, Xingting Liu, Yanfen Ma, Yuling Mi, Weidong Zeng, Jian Li* and Caiqiao Zhang*. Coherent Apoptotic and autophagic activities involved in regression of chicken postovulatory follicles. Aging-US. 2018, 10(4):819-832. doi: https://doi.org/10.18632/aging.101436
5、Xin Lin, Xingting Liu, Changquan Guo, Mengqi Liu, Yuling Mi, Caiqiao Zhang*. Promotion of the prehierarchical follicle growth by postovulatory follicles involving PGE2-EP2 signaling in chickens. Journal of Cellular Physiology. 2018, 1-12. https://doi.org/10.1002/jcp.26844
6、Xingting Liu, Xin Lin, Yuling Mi, Jian Li, Caiqiao Zhang*, Grape seed proanthocyanidin extract prevents ovarian aging by inhibiting oxidative stress in the hens. Oxidative Medicine and Cellular Longevity. Vol. 2018, Article ID 9390810, 16 pages, 2018. doi:10.1155/2018/9390810.
7、R. X. Li, J. Li, S. Y. Zhang, Y. L. Mi, C. Q. Zhang*. Attenuating effect of melatonin on lipopolysaccharide-induced chicken small intestine inflammation. Poultry Science. 2018,97(7):2295–2302 (SCI, IF 2.216) https://doi.org/10.3382/ps/pey084
8、Dan Zhao, Imdad Hussain Leghari, Jian Li, Yuling Mi and Caiqiao Zhang*. Isolation and culture of chicken growing follicles in 2- and 3-dimensional models. Theriogenology. 2018, 111: 43-51. DOI: https://doi.org/10.1016/j.theriogenology.2018.01.012
9、J. Li, J. Li Jr, S. Y. Zhang, R. X. Li, X. Lin, Y. L. Mi, C. Q. Zhang*. Culture and characterization of chicken small intestinal crypts. Poultry Science. 2018, 97(5):1536–1543.
10、Xing-ting Liu, Xin Lin, Yu-ling Mi, Wei-dong Zeng, Caiqiao Zhang*. Age-related changes of yolk precursor formation in the liver of laying hens. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2018, 19(5):390-399.
11、J. Li, R. X. Li, G. Liu, C. F. Lv, Y. L. Mi, and C. Q. Zhang*. Effect of melatonin on renewal of chicken small intestinal mucosa. Poultry Science. 2017, 96(8):2942-2949. DOI: 10.3382/ps/pex085
12、Dan Zhao, Caifeng Lv, Guang Liu, Yuling Mi* and Caiqiao Zhang* Effect of estrogen on chick primordial follicle development and activation. Cell Biology International. 2017, 630–638.
13、G Liu, R Li, C Guo, D Zhao, Y Mi, J Li* and C Zhang*. Inhibitory effect of melatonin on formation of the chicken primordial follicles. Pakistan Veterinary Journal. 2017, 37(3): 263-268.
14、L. Wang, J. Li, J. Li Jr., R. X. Li, C. F. Lv, S. Li, Y. L. Mi, and C. Q. Zhang*. Identification of the Paneth cells in chicken small intestine. Poultry Science. 2016, 95:1631–1635. doi: http://dx.doi.org/10.3382/ps/pew079
15、Jun Li, Dan Zhao, Changquan Guo, Jian Li, Yuling Mi*, Caiqiao Zhang*. Involvement of Notch signaling in early chick ovarian follicle development. Cell Biology International. 2016, 40(1):65-73 DOI: 10.1002/cbin.10538.
16、Fuyin Hou, Min Xiao, Jian Li, Weidong Zeng, Caiqiao Zhang, Yuling Mi*. Ameliorative effect of grape seed proanthocyanidin extract on cadmium-induced meiosis inhibition during oogenesis in chicken embryos. The Anatomical Record. 2016, 299 (4):450-460.
17、Kai Jin, Xin Ye, Sha Li, Bo Li, Caiqiao Zhang, Changyou Gao, Juan Ye. A biomimetic collagen/heparin multi-layered porous hydroxyapatite orbital implant for in vivo vascularization studies on the chicken chorioallantoic membrane. Graefes Arch Clin Exp Ophthalmol, 2016 , 254 (1) :83-89. DOI 10.1007/s00417-015-3144-6
18、Imdad Hussain Leghari, Dan Zhao, Yuling Mi and Caiqiao Zhang*. Isolation and culture of chicken primordial follicles. Poultry Science.2015,94:2576-2580.
19、I. H. Leghari, J. Li, W. Zeng, Y. Mi* and C. Zhang*. Comparative study of reproductive organs and egg quality characteristics in Hyline and domestic layer breeds. Pakistan Veterinary Journal. 2015, 35(3):315-320.
20、侯福銀,宓君鵬,劉興廷,李劍,米玉玲*,張才喬. 原花青素對鎘引起的雞胚睪丸氧化損傷的緩解作用。生態毒理學報,2015,10(4):138-145, 2015
浙江大學
21、趙丹,劉廣,郭長權,李劍,米玉玲,張才喬*. 雌激素對雞早期卵巢發育的影響。2015,中國科技論文線上. http://www.paper.edu.cn/releasepaper/content/201512-641.
22、俞萍,李劍,米玉玲,張才喬*. 雞早期卵泡發育的研究。2015,中國科技論文線上. http://www.paper.edu.cn/releasepaper/content/201512-649.
23、Yuling Mi, Bin He, Jian Li, Caiqiao Zhang*. Progesterone regulates chicken embryonic germ cell meiotic initiation independent of retinoic acid signaling. Theriogenology. 2014, 82(2):195–203.
24、Jun Li, Imdad Hussain Leghari, Bin He, Weidong Zeng, Yuling Mi, Caiqiao Zhang*. Estrogen stimulates expression of chicken hepatic vitellogenin II and very low density apolipoprotein II through ERα. Theriogenology. 2014, 82(3): 517-524.
25、H. Wang, C. Zhang, Y. Mi, M*. T. Kidd. Copper and lysine-amino acid density responses in commercial broilers. Journal of Applied Poultry Research. 2014, 23(3):470-477.
26、Bin He, Yuling Mi*, Caiqiao Zhang*. Gonadotropins regulate ovarian germ cell mitosis/meiosis decision in the embryonic chicken. Molecular and Cellular Endocrinology. 2013, 370(1-2):32-41. DOI: 10.1016/j.mce.2013.02.010
27、Minli Yu, Ping Yu, Imdad Hussain Leghari, Chutian Ge, Yuling Mi, Caiqiao Zhang*. Raldh2, the enzyme for retinoic acid synthesis, mediates meiosis initiation in germ cells of the female embryonic chickens. Amino Acids. 2013, 44(2):405-412.
28、Yudong Jia, Jinxing Lin, Yuling Mi, Caiqiao Zhang*. Prostaglandin E2 and insulin-like growth factor I interact to enhance proliferation of theca externa cells from chicken prehierarchical follicles. Prostaglandins and Other Lipid Mediators. 2013, 106:91-98.
29、Yuling Mi, Longlong Tu, Huimin Wang, Weidong Zeng, Caiqiao Zhang* Supplementation with quercetin attenuates 4-nitrophenol-induced testicular toxicity in adult male mice. The Anatomical Record. 296(10):1650-1657, 2013.
30、Lin Jinxing, Yunjie Mao, Yuling Mi, Caiqiao Zhang*. Effect of Ghrelin on development of chicken prehierarchical follicles. Chinese Journal of Animal and Veterinary Sciences. 43:22-28, 2013
31、Jie Li, Jun Li, Sha Li, Bin He, Yuling Mi, Hongcui Cao, Caiqiao Zhang*, Lanjuan Li*. Ameliorative effect of grape seed proanthocyanidin extract on thioacetamide-induced mouse hepatic fibrosis. Toxicology Letters. 2012, 213(3):353–360.
32、Chutian Ge, Minli Yu, Caiqiao Zhang*. G protein-coupled receptor 30 mediates estrogen-induced proliferation of primordial germ cells via EGFR/Akt/β-catenin signaling pathway. Endocrinology. 2012, 153(7): 3504-3516. doi:10.1210/en.2012-1200
33、Bin He, Jinxing Lin, Jie Li, Yuling Mi, Weidong Zeng, Caiqiao Zhang*. Basic fibroblast growth factor suppresses meiosis and promotes mitosis of ovarian germ cells in embryonic chickens. General and Comparative Endocrinology. 2012, 176(2):173-181. DOI:10.1016/j.ygcen.2012.01.012
34、Chutian Ge, Jian Ye, Qin Wang, Caiqiao Zhang*, Jun-Mo Yang, Guoying Qian. Polycyclic aromatic hydrocarbons suppress meiosis in primordial germ cells via the AHR signaling pathway. Toxicology Letters. 2012, 210(3):285-92.
35、Minli Yu, Chutian Ge, Weidong Zeng, Yuling Mi and Caiqiao Zhang*. Retinoic acid promotes proliferation of chicken primordial germ cells via activation of PI3K/Akt-mediated NF-κB signaling cascade. Cell Biology International. 2012, 36(8):705-712.
36、Jinxing Lin, Yudong Jia, Weidong Zeng, Yuling Mi, Caiqiao Zhang*. Basic FGF promotes proliferation of ovarian granulosa cells in the laying chickens via FGFR1 and PKC pathway. Reproduction in Domestic Animals. 2012, 47(1):135-142 (SCI, IF 1.400) DOI: 10.1111/j.1439-0531.2011.01813.x.
37、Tongliang Bu, Yudong Jia, Jinxing Lin, Yuling Mi*, Caiqiao Zhang*. Alleviative effects of quercetin on germ cells intoxicated by 3-methyl-4-nitrophenol from diesel exhaust particles. Journal of Zhejiang University-SCIENCE B (Biomed & Biotechnol). 2012, 13(4):318-326.
38、Minli Yu, Kun Guan, Caiqiao Zhang*. The promoting effect of retinoic acid on proliferation of chicken primordial germ cells by increased expression of cadherin and catenins. Amino Acids. 2011, 40(3):933-941.
39、Yudong Jia, Jinxing Lin, Yuling Mi, Caiqiao Zhang*. Quercetin attenuates cadmium-induced oxidative damage and apoptosis in granulosa cells from chicken ovarian follicles. Reproductive Toxicology. 2011, 31(4):477-485.
40、Tongliang Bu, Yuling Mi*, Weidong Zeng and Caiqiao Zhang*. Protective effect of quercetin on cadmium-induced oxidative toxicity on germ cells in male mice. Anatomical Record. 2011, 294(3):520-526.
(此處已新增圈子卡片,請到今日頭條客戶端檢視)
41、Jinxing Lin, Yudong Jia, Caiqiao Zhang*. Effect of epidermal growth factor on follicle-stimulating hormone-induced proliferation of granulosa cells from chicken prehierarchical follicles. Journal of Zhejiang University-SCIENCE B (Biomed & Biotechnol). 2011, 12(11):875-883.
42、賈玉東,顏菲菲,曾衛東,張才喬*. 胰島素樣生長因子-I對雞等級前卵泡發育的促進作用. 中國農業科學. 2011,44(20):4295-4301
43、林金杏,毛贇傑,米玉玲,張才喬*. Ghrelin對雞等級前卵泡發育的影響. 畜牧獸醫學報. 2011, 42(9):1220-1226
44、曾衛東,張才喬,米玉玲,蔣振東. 開設自主性實驗 培養學生的創新能力. 實驗科學與技術. 2011,9(5):114-115,124
45、Yanqun Wu, Chutian Ge, Weidong Zeng and Caiqiao Zhang*. Induced multilineage differentiation of chicken embryonic germ cells via embryoid body formation. Stem Cells and Development.2010, 19(2):195-202.
46、Yudong Jia, Jinxing Lin, Weidong Zeng, Caiqiao Zhang*. Effect of prostaglandin on luteinizing hormone-stimulated proliferation of theca externa cells from chicken prehierarchical follicles. Prostaglandins and Other Lipid Mediators. 2010, 92:77-84.
47、Tu Quang Tan, Chutian Ge, Yuling Mi, Yanmei Jin and Caiqiao Zhang*. Ginsenosides promote proliferation of granulosa cells from chicken prehierarchical follicles through PKC activation and upregulated cyclin gene expression. Cell Biology International.2010, 34(7):769-775.
48、Yuling Mi, Caiqiao Zhang*, Chunmei Li, Shinji Taneda, Gen Watanabe, Akira K Suzuki, Kazuyoshi Taya. Protective effect of quercetin on the reproductive toxicity of 4-nitrophenol in diesel exhaust particles on male embryonic chickens. Journal of Reproduction and Development. 2010, 56(2): 195-199.
49、Yuling Mi, Caiqiao Zhang*, Chunmei Li, Shinji Taneda, Gen Watanabe, Akira K Suzuki, Kazuyoshi Taya. Quercetin attenuates oxidative damage induced by treatment of embryonic chicken spermatogonial cells with 4-nitro-3-phenylphenol in diesel exhaust particles. Bioscience, Biotechnology, and Biochemistry. 2010,74(5):934-938.
50、Hongyun Liu, Weidong Zeng, Ailing Cao, Caiqiao Zhang*. Follicle-stimulating hormone promotes proliferation of cultured chicken ovarian germ cells through protein kinase A and C activation. Journal of Zhejiang University SCIENCE B. 2010, 11(12):952-957.
中國各農業大學教授簡介
杜愛芳(女),浙江大學動科院教授、博導,獸醫一級學科負責人
胡松華,浙江大學動物科學院教授、博導,中獸醫、中藥免疫專家
潘玉春,浙江大學動物科學院教授、博導,動物遺傳育種專家
劉建新,浙江大學求是特聘教授、博導,反芻動物營養調控專家
方維煥,浙江大學動科院副院長、博導,動物預防醫學研究所所長
鄧學梅(女),中國農業大學教授、博導,蛋雞育種專家
梅潔,華中農業大學教授、博士,水產養殖專家
張微(女),中國農業大學教授、博導,反芻動物營養與飼料專家
冷靜(女),苗族,雲南農業大學教授、博導,飼料配方專家
王昕(女),西北農林科技大學教授、博導,動物育種專家